[Buckeye Native 001]

Flagstaff is east-west, if only because Arizona's tallest mountain range (San Francisco Peaks) lie directly north of the city.

Phoenix is divided into east-west depending on which direction from Central Avenue you're heading (streets are east of Central and avenues are west of Central). The suburbs are split into "East Valley" and "West Valley" but I'm not really sure how much of that actually includes the City of Phoenix. It's defined more by the surrounding cities, with Glendale/Peoria/Sun City/Goodyear/Buckeye in the West and Mesa/Chandler/Tempe/Scottsdale/Gilbert in the East

Cincinnati is east-west with Vine Street being the divider, but also has a north-south split because of the Ohio River and Kentucky.