A new cancer-biotech company setting up in CORTEX, which is becoming a hub for cancer tech companies. CORTEX is becoming a hub for cancer tech start-ups.
Feb 18, 2016 – Unleash Immuno Oncolytics Enters License Agreement with Leloir Institute to Develop Immuno-Oncology Products for Cancer Treatment, Gets Established in Saint Louis
Buenos Aires, Argentina – February 18, 2016 –
Unleash Immuno Oncolytics, an immune-oncology company developing oncolytic virus immunotherapy products to treat cancer, today announced that the company has entered a license agreement with INIS Biotech, the tech transfer arm of Fundación Instituto Leloir, and has established operations in Saint Louis, Missouri, USA.
“Immuno-oncology is a very promising field and we are excited to enter this space that could potentially bring truly breakthrough therapies for cancer treatment. Unleash is privileged to license this technology from the Leloir Institute, to leverage this outstanding science to develop innovative immune-oncology therapies” said Unleash’s CEO, Daniel Katzman.
The research work of Dr. Osvaldo Podhajcer´s group led to the development of Unleash’s leading product – UIO-512, an oncolytic virus designed to target both malignant cells and tumor-associated stroma cells. “The stroma, composed by non-malignant cancer-associated fibroblasts, endothelial and immune cells, provides nutrients, structure and helps the malignant cells to grow and disseminate. Cancer-associated stroma cells may account for up to 90% of the tumor mass and are not being specifically and are not targeted by any other current therapies. Thus, targeting the stroma cells is a significant paradigm shift over existing cancer treatments” explained Dr. Podhjacer – Chief, Laboratory of Molecular and Cellular Therapy (Fundación Instituto Leloir, Buenos Aires), Superior Researcher (CONICET) ), Director of the Argentinian Consortium of Genomic Technology.
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