I'm not sure if they franchise but Quebec's
Trois Brasseurs is a small chain of brewpubs that would be a great addition to our city.
They recently opened the anglicized Three Brewers on Yonge St. in Toronto, so they aren't Ontario averse.
We had dinner in the downtown Montreal location last year. The food and beer both were tasty and the brewpub environment wasn't too contrived seeming. I was surprised to later find out it was a chain as it felt pretty original to me.
Maybe Glen Norton over at EcDev could call them up and put us on their expansion radar.
Of course even better would be if a local person, or group, would start up a Hamilton original brewpub and then maybe export it to places like Montreal and Toronto.