I know there has been a business model like this for a couple years now in Montreal. A developer took over two old hotels in the downtown area and altered them to be more appealing to students and then marketed heavily to international students and it seems to be working. Both properties are quite full.
http://www.evomontreal.com/
The prices are similar and Montreal's rental market is very similar to Hamiltons in terms of price. Montreal does have more schools and a bigger student population though but i assume that these are also being marketed as an alternative to Columbia College residences? (not sure what the going rates for those units is)
I actually worked out of an office space in the top of one of the EVO buildings for two years and from what i could tell is that it had a similar turn over to university residences... in that a majority of students just stay for their first year and get settled in the city and then move on to cheaper pastures.
I wonder if a building like this with a smaller student population could sustain on that kind of turnover? I am assuming they put more research into this than we did... or maybe it's a gamble...