I know, we do tease Aurora like the obnoxious younger sibling we once had, but, I believe that 2nd largest, and 2nd most concentrated population in the Denver area stretches east from Broadway to I-225 between the two cities.
Part of the sales pitch for a very powerful transit system along or closely parallel to, Colfax, should include Aurora. A pitch might be that the 10 to 15 minutes (2.5 to 4 miles) at the east end of the system would certainly help Fitz, err
Anschutz and aid redevelopment surround the hospital complex, particularly if the transportation system could T into the I-225 Rail line at the light rail's Colfax Stop.
The West side of I-25 is different, as any north-south line, IMO, should be built south of the Federal Center Station on Kipling (great median right-of-way) to south of US 285.
Perhaps Aurora and Denver might work together (yes, a "little bit of sugar helps the medicine go down...) on the Colfax system, and, Lakewood, piggy back on the technology
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https://www.youtube.com/watch?v=CusLvrjDBXw
The guide wheels would ice up during those rare, but, infamous snow/cold snaps (LOL), but, the presentation is good. The guide wheels narrow the necessary ROW width, and, lower the required support weight if such a system were elevated.
I do believe, however, that a diesel electric bus with variable power abilities to all wheels (electric motor is the differential) might be able to be as effective as this system and not ice up.)
Boulder anyone?