The Genesis Centre at Memorial University of Newfoundland is the cornerstone of our very, very small start-up industry. If I'm generous, I'd say three of the businesses developed there every year survive, and one every two years becomes the global leader in its field.
They're all small, niche businesses.
One that comes to mind (had an event there recently) is Verafin, which provides cyber security for a lot of multinational companies:
https://verafin.com/
And another is SkyHawk Telematics, which your municipal or provincial government probably uses to track its government vehicles.
http://www.skyhawk.co/
Here, most start-ups are, of course, software-as-a-service since it makes absolutely no economic sense to establish manufacturing and the like. We rarely do that for export, and if we do it's usually niche luxury goods (i.e. seal coats, high tops, etc.).
Generally, we don't have an entrepreneurial culture (we're the type of city that, if it burnt down, it'd stay ruined until government rebuilt it) - but it's starting to grow a bit. We're certainly aware of what companies started locally.
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